At least 20 people have been killed, and 35 others injured in an explosion near Cairo’s Coptic Christian Cathedral, Reuters reports citing Egyptian state TV. No one has claimed responsibility for the blast yet.
The latest attack comes two days after two roadside bombs, one in Cairo and one to the north of the capital, left six police officers dead and six others injured.
The blast is thought to have taken place outside St Mark’s Orthodox Cathedral in the Abbassiya area of Cairo.
But locals reported an explosion in the building during prayers.
Security sources suggest an unidentified woman placed an IED inside the cathedral before detonating the bomb remotely.
Video footage from the scene shows parts of the cathedral reduced to rubble.
Ambulances have rushed to the scene.
There was no immediate claim of responsibility.
The explosion happened at around 10am local time (8am GMT).
Local media reported Cairo’s security chief, Khalid Abdel Aal, arrived to inspect the scene.
The cathedral is the seat of the Coptic Orthodox Pope. The Coptic Orthodox Church is the largest Christian church in Egypt and the Middle East.
Egypt’s Coptic Christians make up about 10 per cent of the country’s population.