One person died and 65 people have been injured after the seismic movement which had an epicenter in Lomas.
Houses in the Arequipa region have been destroyed and electricity is out.
In the town of Yauca, Justo Palomino Yucra, 55, was crushed to death.
Provincial mayor of Caravelí, Santiago Neyra confirmed the death following the earthquake.
The Pacific Tsunami Warning Centre said tsunami waves are possible within 300 km of the epicenter along the coast of Peru.
National Weather Service officials also claimed there is a tsunami risk, around 186 miles from the centre.
Peru is located in the Ring of Fire, an area in the Pacific Ocean prone to earthquakes and volcanic eruptions.
The Pacific Tsunami Warning Center said: “Hazardous tsunami waves are forecast for some coasts.”
The statement claimed waves reaching 0.3 meters to one meter “above the tide level are possible for some coasts of Peru.”
It also said waves are forecast to be less than 0.3 meters for the coasts of Chile.
The Pan-American Highway is restricted. Full Report